Drug guide

Diphenhydramine Topical

Diphenhydramine, an antihistamine, is used to relieve the itching of insect bites, sunburns, bee stings, poison ivy, poison oak, and minor skin irritation. Diphenhydramine Topical is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Diphenhydramine Topical comes in cream, lotion, gel, and spray to be applied to the skin. It is used three or four times a day. Follow the directions on the package or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use diphenhydramine exactly as directed. Do not use more or less of it or use it more often than directed by your doctor. Thoroughly clean the infected area, allow it to dry, and then gently rub the medication in until most of it disappears. Use just enough medication to cover the affected area. You should wash your hands after applying the medication. Do not apply diphenhydramine on chicken pox or measles, and do not use it on a child younger than 2 years of age unless directed to do so by a doctor.