Drug guide

Dornase Alfa

Dornase Alfa (DOR-nayse AL-fa) is used in the management of cystic fibrosis. It is used every day with other cystic fibrosis medicines, especially antibiotics, bronchodilators (medicines that open up narrowed breathing passages), and corticosteroids (cortisone-like medicines). Cystic fibrosis is a condition in which thick mucus is formed in the lungs and breathing passages. The mucus blocks the airways and increases the chance of lung infections. The infections then cause the mucus to become even thicker, making it more difficult to breathe. Dornase Alfa will not cure cystic fibrosis. However, when it is used every day, it helps make breathing easier and reduces the number of serious lung infections that require treatment with antibiotics. Dornase Alfa is available only with your doctor's prescription, in the following dosage form: Inhalation Inhalation solution (U.S. and Canada)

Dornase Alfa is used to reduce the number of lung infections and to improve lung function in patients with cystic fibrosis. It breaks down the thick secretions in the airways, allowing air to flow better and preventing bacteria from building up. Dornase Alfa is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Dornase Alfa comes as a solution to inhale by mouth. It usually is taken one or two times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Dornase Alfa exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Dornase Alfa is used to treat cystic fibrosis but does not cure it. Continue to use Dornase Alfa even if you feel well. Do not stop using Dornase Alfa without talking to your doctor. Before you use Dornase Alfa the first time, read the written instructions that come with it. Ask your doctor, pharmacist, or respiratory therapist to demonstrate the proper technique. Practice using the nebulizer while in his or her presence. Only use a nebulizer that is recommended by your doctor.

Brand names:
- Dornase Alfa
- Pulmozyme