Drug guide

Losartan and Hydrochlorothiazide

Losartan ( lo-SAR-tan) and hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide ) is a combination medicine that belongs to the class of medicines called high blood pressure medicines (antihypertensives). It is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled. Losartan works by blocking a substance in the body that causes blood vessels to tighten. As a result, losartan relaxes blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart. Hydrochlorothiazide helps reduce the amount of salt and water in the body by acting on the kidneys to increase the flow of urine; this also helps to lower blood pressure. Losartan and Hydrochlorothiazide also may be used for other conditions as determined by your doctor. Losartan and Hydrochlorothiazide is available only with your doctor's prescription, in the following dosage form(s): Oral Tablets (U.S.)

The combination of Losartan and Hydrochlorothiazide is used to treat high blood pressure. Losartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain chemicals that tighten the blood vessels, so blood flows more smoothly. Hydrochlorothiazide is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.

The combination of Losartan and Hydrochlorothiazide comes as a tablet to take by mouth. It is usually taken once a day with or without food. To help you remember to take Losartan and Hydrochlorothiazide, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Losartan and Hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Losartan and Hydrochlorothiazide controls high blood pressure but does not cure it. Continue to take Losartan and Hydrochlorothiazide even if you feel well. Do not stop taking Losartan and Hydrochlorothiazide without talking to your doctor.

Brand names:
- Hyzaar
- Losartan and Hydrochlorothiazide