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Amlodipine ( am-LOH-di-peen) and benazepril (ben-AY-ze-pril ) combination belongs to the class of medicines called high blood pressure medicines (antihypertensives). It is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled. The exact way in which Lotrel works is not known. Amlodipine is a type of medicine known as a calcium channel blocker. Calcium channel blocking agents affect the movement of calcium into the cells of the heart and blood vessels. Benazepril is a type of medicine known as an angiotensin-converting enzyme (ACE) inhibitor. It blocks an enzyme in the body that is necessary in producing a substance that causes blood vessels to tighten. The action of both medicines together is to relax blood vessels, lower blood pressure, and increase the supply of blood and oxygen to the heart. Lotrel is available only with your doctor's prescription, in the following dosage form: Oral Capsules (U.S.) The combination of Lotrel is used to treat high blood pressure. Amlodipine is in a class of medications called calcium channel blockers. It works by relaxing the blood vessels so the heart does not have to pump as hard. Benazepril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly. The combination of Lotrel comes as a capsule to take by mouth. It is usually taken once a day. To help you remember to take Lotrel, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Lotrel exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Lotrel controls high blood pressure but does not cure it. Continue to take Lotrel even if you feel well. Do not stop taking Lotrel without talking to your doctor. Brand names: - Amlodipine and Benazepril - Lotrel |