Drug guide

Muromonab-CD3

Muromonab-CD3 (myoo-roe-MOE-nab cee-dee-three) is a monoclonal antibody. It is used to reduce the body's natural immunity in patients who receive organ (for example, kidney) transplants. When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Muromonab-CD3 works by preventing the white blood cells from doing this. The effect of Muromonab-CD3 on the white blood cells may also reduce the body's ability to fight infections. Before you begin treatment, you and your doctor should talk about the good Muromonab-CD3 will do as well as the risks of using it. Muromonab-CD3 is to be administered only by or under the immediate supervision of your doctor. It is available in the following dosage form: Parenteral Injection (U.S. and Canada)

Brand names:
- Muromonab-CD3
- Orthoclone OKT3