|
Natalizumab is used to prevent episodes of symptoms in patients with relapsing forms (course of disease where symptoms flare up for a short time, then go away) of multiple sclerosis (MS, a disease in which the nerves do not function properly and patients may experience weakness; numbness; loss of muscle coordination; and problems with vision, speech, and bladder control). Natalizumab has not been shown to help patients with chronic progressive MS (a form of MS in which symptoms are always present and become more severe as time passes). Natalizumab is in a class of medications called immunomodulators. It works by preventing the damage to the brain and nerves that causes the symptoms of MS.
Natalizumab comes as a concentrated solution (liquid) to be diluted and infused (injected over a long time) into a vein by a doctor or nurse. It is usually given once every four weeks in a doctor's office. It will take about one hour for you to receive your entire dose of natalizumab, and you will have to stay in your doctor's office for one hour after your infusion is finished. Natalizumab may cause serious allergic reactions that may happen within 2 hours after the beginning of an infusion. A doctor or nurse will monitor you during this time to be sure you are not having a serious reaction to the medication. Tell your doctor or nurse if you experience any of the following symptoms during or shortly after your infusion: hives; rash; itching; difficulty breathing or swallowing; dizziness; fainting; upset stomach; blurred vision; fever; chills; flushing; and chest pain. Natalizumab controls the symptoms of MS, but does not cure it. Keep all appointments to receive natalizumab even if you feel well. |